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In 10 screen(s) in human haploid (HAP1) cells EIF4B was found to be regulator. Specifically, EIF4B was found to negatively affect the abundance of glycosylated LAMP1, GNB1, Histone H3(K27) trimethylation and deY-Tubulin and positively affect the abundance of phospho-ERK, phospho-AKT, phospho-AKT in KCTD5 knockout, phospho-p38, CD47 and HMGCR