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In 8 screen(s) in human haploid (HAP1) cells E2F3 was found to be regulator. Specifically, E2F3 was found to negatively affect the abundance of phospho-ERK, GNB1, Histone H2A(K119) crotonylation, non-phospho-beta-Catenin, phospho-p38, HMGCR, deY-Tubulin and CD47