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In 8 screen(s) in human haploid (HAP1) cells CTBP2 was found to be regulator. Specifically, CTBP2 was found to negatively affect the abundance of phospho-AKT and HMGCR and positively affect the abundance of glycosylated LAMP1, Histone H3(K27) trimethylation, PD-L1, IRF1, CD47 and PD-L1 in CMTM6 knockout