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In 5 screen(s) in human haploid (HAP1) cells COX10 was found to be regulator. Specifically, COX10 was found to negatively affect the abundance of Histone H3(K27) trimethylation and Histone H2A(K119) crotonylation and positively affect the abundance of glycosylated LAMP1, PD-L1 in CMTM6 knockout and deY-Tubulin