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In 5 screen(s) in human haploid (HAP1) cells COQ3 was found to be regulator. Specifically, COQ3 was found to negatively affect the abundance of Histone H2A(K119) crotonylation and positively affect the abundance of phospho-AKT, PD-L1 in CMTM6 knockout, HMGCR and deY-Tubulin