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In 7 screen(s) in human haploid (HAP1) cells CHD8 was found to be regulator. Specifically, CHD8 was found to negatively affect the abundance of CD47 and positively affect the abundance of phospho-ERK, GNB1, non-phospho-beta-Catenin, PD-L1, PD-L1 in CMTM6 knockout and deY-Tubulin