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In 5 screen(s) in human haploid (HAP1) cells CDK4 was found to be regulator. Specifically, CDK4 was found to negatively affect the abundance of glycosylated LAMP1, GNB1 in KCTD5 knockout, Histone H2A(K119) crotonylation, CD47 and PD-L1 in CMTM6 knockout