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In 9 screen(s) in human haploid (HAP1) cells CDH2 was found to be regulator. Specifically, CDH2 was found to negatively affect the abundance of phospho-ERK, phospho-AKT, GNB1, GNB1 in KCTD5 knockout, phospho-p38 and PD-L1 in CMTM6 knockout and positively affect the abundance of glycosylated LAMP1, non-phospho-beta-Catenin and deY-Tubulin