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In 6 screen(s) in human haploid (HAP1) cells CAB39 was found to be regulator. Specifically, CAB39 was found to negatively affect the abundance of phospho-ERK and PD-L1 and positively affect the abundance of glycosylated LAMP1, GNB1, GNB1 in KCTD5 knockout and Histone H3(K27) trimethylation